Back in 2004, Ota and colleagues identified a novel gene, designated “Chromosome 13 open reading frame 25 (C13orf25)”, which was overexpressed in B-cell lymphoma cell lines and diffuse large B-cell lymphoma patients with 13q31-q32 amplifications in cells from 70 patients [79]. This evidence concerns the gene MIR17HG and B-cell non-Hodgkin lymphoma.