STAT6 and allergic rhinitis: It has been documented that phosphorylated STAT6 but not STAT1 and STAT3 are significantly increased in the sinonasal mucosa after allergen stimulation in a murine model of chronic eosinophilic airway inflammation [165,166], and STAT6 gene silencing ameliorated allergic rhinitis [167] and inhibited allergic airways inflammation [168,169].