However, due to the values obtained for CD3+CD4− lymphocytes (p = 0.5072, AUC = 0.5850), NK cells (p = 0.2125, AUC = 0.6599), granulocyte percentages (p = 0.1000, AUC = 0.7109), the NK/T ratio (p = 0.2540, AUC = 0.6463), and the expression of CD62L (p = 0.4381, AUC = 0.6048) and CD11a (p = 0.3067, AUC = 0.6381) in B lymphocytes, these measures would not be able to discriminate between healthy donors and RA patients. This evidence concerns the gene CD4 and rheumatoid arthritis.