To achieve this goal, the following tasks were set: (1) to characterize the concentration thresholds for the aggregate formation by GS using a set of physical and chemical methods; (2) to evaluate the antimicrobial activity of new surfactants; (3) to optimize liposomal compositions during modification with GS; (4) to evaluate the ability of the modified liposomes to get in the brain; and (5) to test cationic liposomes for the therapy of transgenic mice with AD model (APP/PS1) in a behavioral memory test and histological analysis of amyloid beta (Aβ) plaques. The gene discussed is APP; the disease is Alzheimer disease.