SETD2 and nonpapillary renal cell carcinoma: Through analyzing the TCGA transcriptome and mutational data of ccRCC patients, we found that the FoxP3 mRNA level was significantly and positively correlated with mutations in the SET domain containing 2 (SETD2; p < 0.0001) and BRCA1 associated protein 1 (BAP1; p < 0.001) genes (Figure 1B).