However, unlike Sell K et al., who mainly focused on the aggregation of Tregs, our results might be associated not only with excessive Tregs but also with the overexpression of FoxP3 in ccRCC tumor tissues caused by BAP1- or SETD2-mutant, and our findings might not have been reported yet. Here, SETD2 is linked to nonpapillary renal cell carcinoma.