HIF1A and myocardial infarction: Moreover, the expression of HIF-1α induced by dimethyloxaloylglycine stimulated TRPC1 expression in primary mouse coronary artery ECs and improved cardiac function of TRPC1fl/fl, as compared to TRPC1EC−/− mice after MI, which was associated with an increased capillary density, decreased infarct size and improved ejection fraction.