Dysbiosis may have a causative role in lung diseases by upregulating inflammatory signals (such as nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB), Ras, IL-17, and phosphoinositide 3-kinase (PI3K)) [67,71,72,73,74] or by suppressing the production of TNF and interferon-gamma (IFNγ) in response to pathogen presence in the lower respiratory tract [58,75]. This evidence concerns the gene IFNG and lung disorder.