However, a recent study using a δ-opioid receptor knockout mice (e.g., for Nav1.8), which express about 50–70% less δ-opioid receptor in neurons of the dorsal root ganglia (considering that Nav1.8 is expressed in over 90% of peripheral nociceptors and mechanosensors), revealed that the anti-allodynic effect of SNC80 in the NTG model of migraine was only slightly reduced [141]. Here, SCN10A is linked to migraine disorder.