Linc00518 was found to increase the resistance of MCF-7 cells to paclitaxel by reducing paclitaxel-induced apoptosis through the miR-199a/MRP1 axis, and linc00518 downregulation reduced multidrug resistance by regulating the miR-199a/MRP1 axis in breast cancer [147]. The gene discussed is ABCC1; the disease is breast cancer.