This bile acid is able to inhibit the binding between SARS-CoV-2 and its receptor ACE2, as well as to reduce the levels of pro-inflammatory cytokines (TNF-α, IL-2, IL-1β, IL-6 and IL-4), causing anti-inflammatory, antioxidant and anti-apoptotic effects and reducing the alveolar fluid accumulation observed during the acute respiratory distress syndrome associated with COVID-19 [75]. The gene discussed is ACE2; the disease is COVID-19.