In COVID-19 patients, 8-isoprostaglandin F2 alpha levels, considered as a marker of oxidative tissue damage, were elevated [62], and in a recent study [38], COVID-19 patients showed significantly higher values of hydrogen peroxide (H2O2) and NADPH oxidase 2 (NOX2) activity in serum, as well as TNF-α and IL-6. Here, CYBB is linked to COVID-19.