ZBTB16 and acute myeloid leukemia: Furthermore, the injection of GCSF into the CYT-alone (CYT+GCSF) or in combination with the AML-treated group (AML+CYT+GCSF) significantly increased the Plzf level compared to the relevant groups without GCSF 4 weeks and 5.5 weeks post (Figure 5D,E).