Other studies using the same methodological approach have also shown exclusion mechanisms in CCOC, particularly in patients with ARID1A mutation (ARID1Amut) [7,16] In particular, Devlin et al. [16] showed that patients with CCOC and ARID1A wild type (ARID1Awt) contained significantly higher amounts of CD3+, CD8+, and CD4+ cells in the stromal area compared to ARID1Amut tumours. This evidence concerns the gene CD4 and neoplasm.