In particular, beta cells of diabetics exhibited decreased expression of genes encoding molecular chaperones belonging to the heat shock families Hsp70 (HSPA1B, HSPA7, and HSPA8) and Hsp90 (HSP90AA1 and HSP90AB1) as well as co-chaperones (BAG3 and ST13) and nucleoporins (NDC1, NUP160, and POM121C). Here, HSPA8 is linked to diabetes mellitus.