Furthermore, several protein folding regulating genes such as RPS19BP1, RAE1, MTOR, POM121C, and GFER in Dataset 1 and NUP35, NUP58, and NUP107 in Dataset 2 have been found to be up-regulated in beta cells from T2D patients when compared to non-diabetics. This evidence concerns the gene GFER and type 2 diabetes mellitus.