The inflammatory biomarker MCP-1 and oxidative stress biomarkers 8-OHdG and TAC, although they were significantly higher in IC/BPS than in the normal and PRES subgroups, and did not provide a diagnostic value between patients with IC/BPS and the BOO, DO, or HSB subgroups. The gene discussed is CCL2; the disease is Bartsocas-Papas syndrome 1.