Among the women with IC/BPS, urinary levels of MIP-1β and TNF-α had the highest AUC to predict IC/BPS from the controls, whereas patients with Hunner’s IC had significantly higher urinary levels of IL-8, CXCL10, BDNF, IL-6, and RANTES than non-Hunner’s IC [33]. The gene discussed is BDNF; the disease is Bartsocas-Papas syndrome 1.