IL22 and psoriasis: In a similar way, they and Sa et al. have developed psoriasis models using IL-20 subfamily cytokines, such as IL-19, IL-20, IL-22, and IL-24, or a mixture of IL-17, IL-22, and TNFα [224,225], which induced hypogranulosis, parakeratosis, and altered the expression of the genes involved in psoriasis.