One of the first reports was published by Al-Shali et al. [12], in which no coding sequence mutations in either LMNA or PPARG were found in a female FPLD patient; instead, a novel A > G mutation at position −14 of intron B upstream of PPARG exon 1 within the promoter of the PPARγ4 isoform was discovered. Here, PPARG is linked to familial partial lipodystrophy.