TLR4 and metabolic dysfunction-associated steatotic liver disease: The ingestion/administration of probiotics may result in a decrease in harmful bacteria by modulating the composition of the intestinal microbiota and its metabolites and improving the barrier function, thereby decreasing the translocation and concentration of serum LPS, which delay the progression of NAFLD via the negative signaling of LPS/TLR4 [103,105,110] as well as the oxidative stress caused by the interaction between LPS and TLR4 [108].