Cells infected with HSV-1 KOS at multiplicity of infections (MOIs) of 1 and 10, HSV-1 532 at MOIs of 0.01 to 1 and HSV-2 at MOIs of 10 and 100, in contrast, exhibited very bright LC3B staining; the fluorescence intensity profiles were composed of numerous robust peaks, which were separated and cytoplasmic or more confluent and perinuclear. Here, MAP1LC3B is linked to infection.