After inputting miR-7-5p, IP-10 (CXCL10), CRP and glucose into IPA software version 9.0 imitating a diabetic state, it was predicted, through published knock-out studies that miR-7-5p has anti-angiogenic effects and is significantly upregulated in T1DM patients (Figure 4). This evidence concerns the gene CRP and type 1 diabetes mellitus.