INS and type 1 diabetes mellitus: A large study from the Diabetes-Patienten-Verlaufsdokumentation (DPV) registry involving multiple diabetes centers in Germany, Austria, Switzerland, and Luxembourg found that the early initiation of insulin pump therapy within 6 months of diagnosis in people with childhood-onset T1D was associated with a better cardiovascular risk profile compared to those with delayed CSII initiation within 2–3 years of T1D diagnosis [86].