PRRT2 and asthma: Since PKCθ is necessary for efficient activation of transcription factors such as NFAT, NF-κB, GATA3, and STAT6 during allergic asthma reactions [22,23,31], we investigated whether BGE or C20 (a specific PKCθ inhibitor) could inhibit the activation of PKCθ and asthma-associated transcription factors in PMA/Iono-stimulated EL4 cells.