In osteoporosis-related alveolar bone resorption, IL-6—an osteoclastogenesis-promoting cytokine—promotes the conversion of forkhead box P3 (FoxP3) T cells to T helper 17 (Th17) cells, which guard against germs but induce osteoclast formation and thus, bone injury [125,126,127]. The gene discussed is FOXP3; the disease is osteoporosis.