Dme-mir-137-3p was also found to be upregulated in an α-synuclein overexpression-based Drosophila PD model and regulated several members of the neuroactive-ligand receptor interaction pathway (dopamine receptor (D2R), γ-aminobutyric acid receptor (GABA-B-R3), and N-methyl-D-aspartate receptor (Nmdar2) dysregulated in PD flies [35]. Here, DRD2 is linked to Parkinson disease.