Podoplanin is a type I transmembrane sialomucin-like glycoprotein that is located in certain types of human cancers, including squamous cell carcinoma, brain cancer, glioblastoma, osteosarcoma, bladder cancer and others (in studies cited by Miyata et al., 2017) [131], as well as several normal tissues. This evidence concerns the gene PDPN and cancer.