TRPM2 and neoplasm: Furthermore, the stemness of tumor cells was also closely associated with TRPM2: the expression level of TRPM2 was significantly positively correlated to the DNA methylation-based stemness score (DNAss) in 16 tumor types (Figure 6D), including LGG, LUAD, COAD, BRCA, ESCA, STES, KIRP, STAD, PRAD, HNSC, THYM, THCA, READ, PAAD, UVM, and CHOL.