TRPM2 and glioblastoma: On the other hand, a significant downregulation of TRPM2 expression was found in ACC, GBM, and LGG, and no statistically significant change was observed in the case of KICH, PCPG, THCA, and THYM (Figure 1A. Please see the complete list of the TCGA cancer-type abbreviations in Supplementary Materials File S1).