Other background information, such as the positive correlation of TRAIL sensitivity with FUT3 and FUT6 mRNA levels [24,50] and the fact that TRAIL resistance originates from GMDS gene mutation, which accelerates tumour growth due to evasion of immune surveillance [25], also prompted us to investigate the TRAIL–glycosylation relationship in CRC. Here, TNFSF10 is linked to colorectal carcinoma.