Lastly, the most recent study showed that curcumin significantly decreased weight (p = 0.03), BMI (p = 0.03), fasting glucose (p = 0.002), serum insulin (p = 0.02), insulin resistance (p = 0.02), total cholesterol (p = 0.001), LDL-cholesterol (p = 0.001), and total-/HDL-cholesterol ratio (p < 0.001). This evidence concerns the gene INS and Insulin resistance.