PLOD1 and polycystic ovary syndrome: Finally, one RCT examined the effects of the Mediterranean diet on various outcomes of PCOS and demonstrated improved overall menstruation rates, decreased total testosterone levels, decreased LH levels, improved anthropometric measures of weight, improvement of various lipid parameters including decreased triglycerides, total cholesterol, and LDL cholesterol, reduction in blood glucose, and improved HOMA-IR levels [38].