These include EGFR [24,25,26,27], commonly associated with amplification of the gene [25,26], SOX11 [18,19,28] and INSM1 [16], involved in different stages of normal embryonal neurogenesis [28,29], MEOX2 [11], associated with a poor prognosis and a subset of mesenchymal subtype GBMs [30], and CD34, an adhesive molecule detected in a subset of low grade epilepsy associated glioneuronal tumours [22], pleomorphic xanthoastrocytomas [31], and a subset of GBMs [32]. The gene discussed is INSM1; the disease is epilepsy.