In reality, CTA is a useful diagnostic tool, but it involves ionizing radiation, which is not only carcinogenic in the long term [41] but may also contribute to the destabilization of the coronary plaques by several mechanisms, such as increasing the permeability of coronary endothelium [42,43] and maintaining inflammation due to Nuclear factor kappa B (NF-κB) [44,45], eventually becoming an important cofactor in causing acute myocardial infarction, sudden death, and angina [46,47]. The gene discussed is NFKB1; the disease is myocardial infarction.