The latest study, including 280 COVID-19 patients classified into four different severity groups, revealed significant differences in galectin-3 levels among patients of varying COVID-19 severity, with the highest levels of galectin-3 but also IL-1β, TNF-α, IL-12, and IL-10 in the critical (highest severity) [123] group. The gene discussed is IL1B; the disease is COVID-19.