In a similar study of a working population of 1566 reported in 2019, the Spearman’s correlation coefficient between D-12 and the CAT was 0.398; between D-12 and E-RS, it was 0.274; and between the CAT and E-RS, it was 0.446 [31], so it can be assumed that the correlation coefficient is quite good in subjects with COPD. The gene discussed is CAT; the disease is chronic obstructive pulmonary disease.