YY1 knockdown in an AML sample and AML cell lines restored/increased mRNA and protein expression of C/EBP family members, including C/EBPα, C/EBPε, and C/EBPδ, involved in normal and leukemic myelopoiesis [113], and promoted the expression of pro-myeloid growth factor receptors such as GM-CSFr and G-CSFr in HL-60 and of GM-CSFr in OCI-AML3. This evidence concerns the gene YY1 and acute myeloid leukemia.