YY1 and acute myeloid leukemia: The knockdown of YY1 protein in the AML patient sample and in the HL-60 and OCI-AML3 cell lines led to an increase in the expression of genes associated with myeloid differentiation, including myeloid transcription factors (C/EBPε, C/EBPδ), myeloid growth factors receptors (GM-CSFr, G-CSFr), and the granulocytic differentiation marker (CD11b).