Betulinic acid (Figure 7) is a pentacyclic triterpenoid primarily derived from the bark of white birch trees and has been shown to promote mitochondrial oxidative stress, regulate transcription factors, and inhibit STAT and activator of the NF-κB signaling pathway in prostate, breast, colorectal, and lung cancers [378]. This evidence concerns the gene SOAT1 and lung carcinoma.