Further studies will explore if the L-pampoTM-containing vaccine can also synergize with other ICIs, such as an anti-CTLA-4 antibody, if this combination works in other tumor models such as prostate or colon cancer, and if L-pampoTM, alone or in combination with ICI, affects T-cell memory. The gene discussed is CTLA4; the disease is malignant colon neoplasm.