Complete tumor necrosis rates were: 62.5% (5 of 8) in patients with an initial AFP level < 100 ng/mL and decline of ≥10.2 ng/mL (group 1); 21.3% (13 of 61) in patients with an initial AFP level < 100 ng/mL and decline of <10.2 ng/mL (group 2); 16.7% (2 of 12) in patients with an initial AFP level > 100 ng/mL and decline of ≥340.5 ng/mL (group 3); and null in 20 patients with an initial AFP level > 100 ng/mL and decline of <340.5 ng/mL (group 4), respectively (p = 0.003). Here, AFP is linked to neoplasm.