In the subgroup with an AFP < 100 ng/mL, a prediction of complete tumor necrosis based on ΔAFP was associated with an AUC of 0.604 (95% confidence intervals 0.452 to 0.756, p = 0.180) and an optimal cut-off of ≥10.2 ng/mL (Figure 1). Here, AFP is linked to neoplasm.