The largest subset of cells was characterized by the expression of prostate cancer-specific proteins, PSA and PSMA, as well as EpCAM and AR defining those as prostate-derived epithelial CTCs, but individual cells differed in their expression of the mesenchymal marker vimentin (EPI.CTCs and pEMT.CTCs). The gene discussed is KLK3; the disease is Familial prostate cancer.