Some of the novel decreased proteins have been described to exert anti-apoptotic and survival effects in different malignancies [30,31,32], including cHL: LMNB1 (R) and DSG1 (P); in MCL: DFFB (R) and ITGB2 (P); and ALCL: HSPA7 (R) and CARD11 (P). Here, ITGB2 is linked to mantle cell lymphoma.