The study by Northcott et al. [25] employed the Cis Expression Structural Alteration Mapping (CESAM) technique to demonstrate that enhancer hijacking of growth factor independent 1 (GFI1) or GFI1B proto-oncogenes potentiate the effects of MYC amplification and further promotes tumor proliferation in group 3 medulloblastomas. The gene discussed is GFI1; the disease is medulloblastoma.