Six cell lines, including four Burkitt lymphoma cell lines, Daudi, Namalwa, Ramos, Raji, a mantle cell lymphoma cell line JeKo-1, and an acute lymphoblastic leukemia cell line RS4;11 (referred to as RS4 hereon), were evaluated for the expression of matriptase, prostasin, and HAIs at the mRNA level. The gene discussed is PRSS8; the disease is Burkitt lymphoma.