The significantly regulated pathways included the following 14 genes: AKT1, ATM, BCL2, CAV1, CCND1, CDKN1DIAPH1, ERBB2, FAS, HIF1A, IGF1R, ITGA3, MDM2 and VAV3. The pathways with the most affected genes reported in the analysis were Pathways in cancer, affected by 10 genes: AKT1, BCL2, CCND1, CDKN1B, ERBB2, FAS, HIF1A, IGF1R, ITGA3 and MDM2. The gene discussed is VAV3; the disease is cancer.