Our analyses identified a considerable amount of research highlighting the potential of radiomics methodologies for predicting important genetic biomarkers in gliomas, such as the epidermal growth factor receptor (EGFR), isocitrate dehydrogenase 1 (IDH1), O^6-methylguanine-DNA methyltransferase (MGMT), and v-Raf murine sarcoma viral oncogene homolog B (BRAF) mutations, using various MRI contrasts, radiomic features, and machine-learning algorithms (in the so-called radiogenomic field). This evidence concerns the gene MGMT and central nervous system cancer.