For BC where CD34-positive stromal cells are present inside the tumor stroma, some authors suggested that CD34-positive BC stromal cells/telocytes are precursors for αSMA-positive stromal CAFs [27], and this may explain divergent expression of two markers from the ability of CD34-positive stromal cells to dedifferentiate into αSMA-positive CAFs. Here, ACTA1 is linked to breast cancer.