MDS/MPN with thrombocytosis and SF3B1 mutation (MDS/MPN-T-SF3B1) is defined as thrombocytosis (platelets > 450,000 × 109/L) with anemia with minimal blasts (<1% in PB and <5% in BM) [3]. This evidence concerns the gene SF3B1 and myeloproliferative neoplasm.