Notably, cancer-associated stromal cells can stimulate epithelial cells to transform into malignant cells owing to the release of growth factors, chemokines, and cytokines, including fibroblast growth factor (FGF), platelet-derived growth factor (PDGF-BB), transforming growth factor β (TGFβ), interleukin-6 (IL-6), IL-8, and chemokine (C-X-C motif) ligand 7 (CXCL7) [21]. The gene discussed is IL6; the disease is cancer.