As early as the hyperplasia stage, there are 110 PCGs (70%) and 44 lncRNA genes (28%) from cluster 1, 79 PCGs (67%) and 38 lncRNA genes (32%) from cluster 2, and 479 PCGs (83%) and 97 lncRNA genes (17%) from cluster 3 that are exclusively differentially expressed in PTHrP WT tumor compared to tumor-free controls (Figure S4). This evidence concerns the gene PTHLH and neoplasm.