IL6 and infection: The infection of these cells may worsen the local inflammatory response (activation of macrophage, cytokine storm with high levels of interleukin 6 (IL-6), release of tissue factor, and activation of coagulation) leading to microcirculatory dysfunction, renal hypoperfusion, and tubular injury (viral-induced tubular or glomerular injury and thrombotic disease) [3,18,19,20].