CD4 and colorectal carcinoma: As listed in Table 4, HHIP was significantly positively correlated with B cell’s biomarkers, CD8 + T cell’s biomarkers, CD4 + T cell’s biomarker, M1 macrophage’s biomarkers, M2 macrophage’s biomarkers, neutrophil’s biomarkers, and dendritic cells’ biomarkers in CRC.