Of the predicted pathogenic (i.e., loss-of-function) BRCA1/2 variants in ovarian cancer that had been discarded (n = 2), one variant is characterized as ‘Pathogenic’ by a single submitter (BRCA1 S324fs*17; ClinVar Variation ID: 946287), while the other is absent from the database (BRCA2 I979fs*12). Here, BRCA2 is linked to ovarian cancer.