Furthermore, high levels of TRP53 or P19ARF connote TRP53 mutations in a tumour, and no consistent differences in the frequency of lymphomas with TRP53 defects were observed between lymphomas from Eμ-MycT/+;Bcl-w+/+ and Eμ-MycT/+;Bcl-w−/− mice (Fig. 3A, B). This evidence concerns the gene TP53 and neoplasm.