Fibroblast growth factor receptors 2 (FGFR2) is expressed in a variety of cancers, such as oral mucosal, esophageal, gastric, colorectal, pancreatic, pulmonary, breast, endometrial, cervical and prostate cancers, to promote the carcinogenesis and cancer progression, thus it has been considered as a new target for cancer treatment38. The gene discussed is FGFR2; the disease is Familial prostate cancer.