Fibroblast growth factor receptors 2 (FGFR2) is expressed in a variety of cancers, such as oral mucosal, esophageal, gastric, colorectal, pancreatic, pulmonary, breast, endometrial, cervical and prostate cancers, to promote the carcinogenesis and cancer progression, thus it has been considered as a new target for cancer treatment38. This evidence concerns the gene FGFR2 and prostate cancer.